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Overall, a new era in obesity care is starting, as multiple effective obesity pharmacotherapies with different mechanisms of action and routes of administration may become available over next years

That said, even with triple the vitamin B12 intake, pregnant mothers serum vitamin B12 dipped into the low-to-mid range of normal in this study

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Future trials or post-marketing data will need to establish whether retatrutide allows dose reduction for maintenance without significant weight regain