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Description

Schrder, S

At the transcriptional level in kidney tubular epithelial cells, glutamine supplementation can downregulate proapoptotic genes (Harakiri [HRK] and BAD) and regulate cytoprotective genes (sulfiredoxin 1 [SRXN1] and heme oxygenase 1 [HMOX1])

Hence, a great variety of diverse agents of natural origin have been found that activate the Nrf2 signalling pathway, but it is likely that many more remain to be discovered

The first patient, a 78-year-old woman, presented with severe incontinence, pelvic pain, and other symptoms that did not improve with different medication regimens