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Sources : Sikiric et al., Curr Pharm Des 2018 | Chang et al., J Appl Physiol 2011 Profil de Scurit & Identit Chimique Spcifications molculaires et donnes de tolrance prclinique BPC-157 Identit Chimique Pentadcapeptide synthtique driv du suc gastrique humain BPC-157 Tolrance & Statut Donnes de scurit issues des tudes prcliniques (rat, souris, lapin, chien) Donnes Prcliniques Publies 6 tudes cls publies dans J Orthop Res, J Appl Physiol, Curr Pharm Des, Growth Horm IGF Res et Am J Sports Med Biomcanique Amlioration significative de la force, rigidit et module d'lasticit du tendon 14 jours Rparation Tendon d'Achille (rat) Migration Acclration dose-dpendante de la migration des fibroblastes tendineux Mcanismes de Rparation Tendineuse Cytoprotection Mdiateur cytoprotecteur novel recrutement vasculaire et gurison du tractus gastro-intestinal Effets Gastroprotecteurs Documents Avis Important Recherche Uniquement Non destin la consommation humaine

FDA advisory committee votes to add popular peptide BPC-157 to drug compounding list The vote is non-binding and still needs sign-off from the FDA

Mechanisms of action: NF-B inhibition: KPV inhibits the activation of nuclear factor kappa-B (NF-B), the master regulator of the inflammatory response