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In all instances only a single peak with 215 nm absorption was detected and collected

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The notation c.11381-?_11524+?del describes a deletion of exon 35 detected via MLPA with the ? indicating that it is unknown how far into the neighboring introns the deletion extends

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The label recommends reducing the dose from 5 mg twice daily to 2.5 mg twice daily when co-administered with these agents, except in patients already on 2.5 mg for age, weight, or creatinine criteria

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