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However, a drug may be toxic in some individuals at concentrations normally tolerated by most other patients

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AAS exposure has been associated with prolongation of ventricular repolarisation, increased dispersion of action potential duration, and reduced heart-rate variability, all of which facilitate arrhythmogenesis ( 7.2 Hepatic toxicity Hepatic dysfunction represents another major adverse effect associated with chronic exposure to supraphysiological androgen levels