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Additional microbiota analysis indicated that the primary cause of these small intestinal injuries may be a corresponding decrease in the abundance of Lactobacillus johnsonii

It can reduce IL-1 and IL-18 expression through the NF-B/NLRP3 pathway, lower blood glucose levels, and improve insulin sensitivity and insulin resistance ( Daotan Decoction has been shown to improve inflammatory responses, insulin resistance, and regulate lipid metabolism, but the mechanisms underlying these effects and their relationship with the gut microbiota remain unclear

[PubMed] [Wiley] [PubMed] 104

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