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Clinically, nocturnal worsening of asthma is associated with increased risk of severe exacerbations and asthma-related mortality, which peak around 04:00 (8, 9)

Introduction Irons role as the protagonist in ferroptosis centres on its ability to cycle between ferrous and ferric states, enabling electron transfer and redox coupling with reactive oxygen species (ROS) generation such as hydrogen peroxide [1]

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