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10.1136/jitc-2022-005940 [DOI] [PMC free article] [PubMed] [Google Scholar] Kawaguchi Y., Sakamoto Y., Ito D., Ito K., Arita J., Akamatsu N., et al

The imbalance between the antioxidant defense system and the generation of oxidants creates oxidative stress which can further cellular damage and compound adverse issues from chronically impaired sleep such as obesity and even neurodegenerative disorders

Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2

Once inside the brain, estrogen stimulates histamine release, so this could be one way that a high-histamine diet in sensitive people might affect energy and concentration levels