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Dietary thiamine restriction in rodents also decreases relative abundance of this family, which is accompanied by reduced fecal butyrate concentrations (61)

Water is not just a solvent here

Part of the cytoplasmic iron is involved in the normal metabolic activities of the cell, such as the activity of mitoferrin expressed in the mitochondrial inner membrane, which transports iron from the cytoplasm to the mitochondria to participate in the synthesis of heme and ironsulfur clusters (Yu et al., 2003)