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Together, glycosylation of Hyl residues, hydroxylation of proline via the complex P4HA/PDI and P3H isoforms, and formation of disulfide bonds initiate aggregation of -chains into a triple helix to form a procollagen molecule that is secreted by a collagen-producing cell into the ECM through a vesicle

These are lyophilized powders that need to be reconstituted with bacteriostatic water (bac water)sterile water for injection containing a preservative, most commonly benzyl alcohol, to prevent bacterial growth

[9] Mirakian R, Leech SC, Krishna MT et al

As scientists deepen our understanding of cellular repair, physicians are discovering better ways to harness the bodys own healing capacity