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however, in phase 1 clinical trial, BIIB078 failed to exert meaningful effects on CNS pathologies and had no significant impact on neurofilament levels but paradoxically increased inflammatory marker CCL26, and its development has been discontinued (van den Berg et al., 2024

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Curcumin dose-dependently reversed PPA-induced deficits in social interaction, repetitive behaviors, anxiety, locomotion, learning and memory, while normalizing oxidative stress, mitochondrial dysfunction and pro-inflammatory signaling, supporting its neuroprotective efficacy in this ASD model (Bhandari and Kuhad, 2015

Research has shown that glutathione plays a critical role in various aspects of our health