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Similar to NPG treatment, deletion of CSE attenuated NAC- and Cys-induced H 2 S generation (Figure S2C) and likewise attenuated the NAC- and Cys-induced mt-roGFP2 response (Figure 3B, left panels), but not the 3MP- and H 2 S-induced mt-roGFP2 responses (Figure 3B, right panels)