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Nonetheless, large-scale clinical trials are required for further validation

Although the above mechanisms have been discovered and confirmed repeatedly, therapeutic strategies should be more specifically targeted to mitochondrial energy defects rather than the neuroprotective effects of antioxidants [52]

Kouitcheu Mabeku LB, Eyoum Bille B, Tchouangueu TF, Nguepi E, Leundji H (2017) Treatment of Helicobacter pylori infected mice with Bryophyllum pinnatum , a medicinal plant with antioxidant and antimicrobial properties, reduces bacterial load

Accompanying symptoms of this condition include local pain, swelling of the lower leg or entire limb, skin redness, as well as Homan's sign, where there is calf pain during dorsiflexion of the foot