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Long-term effects have not been studied in humans or even in animals beyond short-term protocols

The right move is to raise it with your GP or a haematologist, who can review your schedule, rather than quietly adding private injections on top, which leaves no one with the full picture

A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss

Low vitamin B12 levels are more common among those who: If youre experiencing troubling symptoms or believe youre at high risk for a deficiency, raise these concerns with a healthcare provider, who may decide that you should be tested