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Competing interests None declared

Until that point, its use outside of approved clinical trials is not sanctioned by UK regulatory authorities, and the risks of self-administration particularly involving home reconstitution of an unregulated product far outweigh any potential benefit

One tendon attaches to the biceps muscle at the shoulder, and the other at the elbow

Following subcutaneous injection, the peptide enters systemic circulation with bioavailability of 14-19% in rats, while intramuscular administration achieves 45-51% bioavailability in beagle dogs, indicating both route-dependent and species-dependent absorption characteristics