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Along with their trophic and synaptic role in the brain parenchyma, astrocytes are major protagonists in supplying energy to neurons (e.g., lactate), maintaining the homeostatic balance of extracellular pH, neurotransmitters and ions, as well as controlling the reactive oxygen species (ROS) response and intercellular communication and propagation of Ca 2+ signaling

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It were analyzed by sampling the right lumbar level 4,5,6 dorsal root ganglion (RL4,5,6-DRG) and lumbar level 5 spinal cord (L5-SC) from 3 rats of control, morphine, 3 BPC-157 groups at 5 (representative value of phase 1) and 35 min (representative value of phase 2) after the formalin test