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While Semaglutide, also known as Wegovy or Ozempic and Tirzepatide, have dominated weight loss options for quite some time, leading to nearly 25% of body weight loss

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Human and higher primates lack peroxisomal enzyme urate oxidase (uricase) (14) that catalyzes degradation of uric acid to more soluble product allantoin that is easily eliminated by renal excretion in the most other mammals because the genes for uricase have mutated and become dysfunctional (15)

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