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In ADPKD patients, the expression levels of GPX4, SLC3A2, and SLC7A11 are significantly downregulated in the kidneys compared to normal kidneys, while the expression of TFR1 and divalent metal transporter 1 is markedly upregulated

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This shows how different the two types really are

Maintaining a healthy level of antioxidants is important in supporting cellular energy production, immune function & detoxification