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The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)
And it's precisely why a therapy that builds new blood supply directly into damaged tissue can change the equation when nothing else has
In a 2017 study published in the Journal of Molecular Medicine , Hsieh and colleagues reported that BPC-157 promoted angiogenesis in chick chorioallantoic membrane and endothelial tube-formation assays and accelerated blood-flow recovery in a rat hindlimb ischemia model, with the effect attributed to activation of the VEGFR2-Akt-eNOS signaling pathway [1]
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