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Mechanism Involving Nrf2-Keap1 Complex Mitigates the NLRP3 Inflammasome in PD In PD, the NLRP3 inflammasome acts as a central driver of neuroinflammation, perpetuating a self-sustaining inflammatory loop that accelerates the degeneration of dopaminergic neurons

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Basic Clin Pharmacol Toxicol 126:6574 Tunal-Akbay T, Sehirli O, Ercan F, Sener G (2010) Resveratrol protects against methotrexate-induced hepatic injury in rats