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It usually produces less weight loss than tirzepatide, but it has the longest outcomes record in the class: fewer cardiovascular events, slower kidney decline, and years of diabetes-trial safety data

If youre managing a condition, pregnant, or considering IV drips, consult your doctor first

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Clinically, such insights may pave the way for combination strategies, for example pairing JAK inhibitors with modulators of innate immune activation, thereby improving long-term repigmentation stability