doi:10.1101/cshperspect.a009183 Acknowledgments This work was supported by the Chang Gung Memorial Hospital [Grants CMRPD1A0531, CMRPD1C0231, CMRPG391311, CMRPG3A1131] and the Ministry of Science and Technology, Taiwan [Grant NMRPD181001-3]
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observed a high frequency of promoter hypermethylation and progressive loss of GPx3 expression in Barretts esophagus and its associated lesions, and these authors also confirmed the known function of GPx3 as a potent antioxidant [54]
