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The glyoxalase pathway (consisting of glyoxalase I and glyoxalase II enzymes) for detoxification of methylglyoxal, a cytotoxic molecule, also requires GSH in the first reaction step

The biology is interesting enough that ongoing research is warranted, and I'm watching the human trial literature carefully

Interleukin-7 receptor alpha mutational activation can initiate precursor B-cell acute lymphoblastic leukemia

Especially for MOFs, this biomineralization-based platform can even be used to provide mRNA or CRISPR/Cas9 to target resistance genes of microbes, which can generate a break inside the dsDNA of resistant bacteria, rendering them sensitive to antibiotics again [177]