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Cells were seeded into a 384-well glass-bottom black plate (IBL, P384-1.5H-N) and left to adhere overnight

Bose P, Masarova L, Pemmaraju N, Bledsoe SD, Daver NG, Jabbour EJ, Kadia TM, Estrov ZE, Kornblau SM, Andreeff M , Jain N, Cortes JE, Borthakur G, Alvarado Y, Richie MA, Dobbins MH, McCrackin SA, Zhou L, Pierce SA, Wang X, Pike AM, Garcia-Manero G, Kantarjian HM, Verstovsek S

Several studies have also demonstrated the utility of repeat testing and calculation of these indices during the course of hospitalization, including MELD or MDF score at one week, and degree of change

Reduces dark spots and pigmentation