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Table of Contents What is Cagrilintide

IcmF from Cupriavidas metallodurans is an AdoCbl-dependent isobutyryl-CoA mutase fused (IcmF), in which the MeaB domain exists as an independent domain of the target enzyme, which itself harbors two domains, an N-terminal TIM barrel-shaped substrate binding domain and a C-terminal Rossman fold AdoCbl-binding domain (Figure 42B)

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The most common administration-site reactions were injection-site reaction [150 events in 38 (5%) participants] and injection-site erythema [64 events in 42 (6%) participants]