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Amber-tinted light blockers

These phase I oxidative reactions metabolise 210% of paracetamol to a reactive intermediate, N -acetyl- p -benzoquinone imine (NAPQI) which mediates the hepatotoxic effect of paracetamol

Finally, decreased activation of the farnesoid X receptor (FXR) in the distal small intestine by bile acids may also contribute to impaired integrity of the intestinal barrier (127)