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Research applications may include copper peptide pathway models, skin matrix research, collagen pathway studies, extracellular matrix research, peptide-metal complex signaling analysis, cellular response models, matrix-associated signaling comparisons, and structure-function evaluation

The eluted protein was concentrated and further purified by size-exclusion chromatography

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In some embodiments, the otic pharmaceutical formulation comprises between about 80% to about 95% by weight of the triglycerides