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This lipid radical reacts with molecular oxygen to form a lipid peroxyl radical (LOO), which can propagate the chain reaction by abstracting hydrogen atoms from neighboring lipids, leading to the generation of more lipid radicals and peroxyl radicals [9]

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Elevated levels of CRP and MPO frequently co-occur with pro-inflammatory cytokines tumor necrosis factor- (TNF-) and interleukin-6 (IL-6) in experimental diabetic neuropathy models 26,8991 (animal model, in vitro data)

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