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For example, ROS generation is the driver and first requirement for many developmental processes, such as the cell cycle, pollen viability, microspore reprogramming towards sporophytic development, the regulation of female gametophyte patterning, and the maintenance of embryo sac polarity, as well as the prevention of self-pollonation (de Simone et al
Although a plethora of tumor cell mechanosensors have been identified, including focal adhesions, ion channels, actin cytoskeleton, nuclear proteins, and transcription factors, more research is needed to uncover how breast cancer cells convert biophysical signals into biochemical cues to mediate short- and long-term mechanoresponses ( Table 5 )
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