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doi: 10.3389/fimmu.2023.1156774 Received 01 February 2023 Accepted 26 June 2023 Published 11 July 2023 Volume 14 - 2023 Edited by Bowen Wu, Zhejiang University, China Reviewed by Xueping Li, Stanford University, United States

The authors hypothesised that xCT inhibition might be further potentiated by limiting glutamate or glutamine availability, and show that xCT is a compelling therapeutic target for triple-negative tumours