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Long-term outcomes in children with riboflavin transporter deficiency and surveillance recommendations

The main culprits include: Ultraviolet and visible light exposure the strongest daily stimulator Hormonal fluctuations (pregnancy, contraceptives, thyroid changes) Inflammation from acne, eczema or injury (post-inflammatory hyperpigmentation) Ageing and genetics Certain medications or skin trauma Globally, pigmentary disorders affect a significant portion of the population, with surveys showing around half of adults reporting at least one pigmentation concern

[DOI] [PubMed] [Google Scholar] 184.Lamichhane S., Lee S

At this stage, patients typically notice increased hydration and a smoother skin surface