77,83,84 In addition, the expression of ALDH1L2 is upregulated by some certain drugs, such as thapsigargin and tunicamycin, endoplasmic reticulum stress inducers in immortalized human B cells, 85 mitotane, an adjuvant monotherapy used for treating adrenocortical carcinoma, 86 and the indomethacin, an anti-inflammatory agent in breast cancer cells
Theres only anecdotal evidence to support this claim, though, so if you really dislike pineapple, dont force yourself to eat it
Laboratory markers include suppressed free T3 with normal TSH (euthyroid sick syndrome), elevated cortisol, and in severe cases, low LH and FSH indicating hypothalamic suppression
Furthermore, neuroinflammation driven by systemic oxidative stress disrupts the delicate balance of autonomic signaling in the brain, leaving patients stuck in a perpetual, exhausting 'fight or flight' state