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Science, 2011

Mechanism 2: Growth Factor Upregulation BPC-157 stimulates multiple growth factors involved in tissue repair: FGF (Fibroblast Growth Factor) promotes fibroblast activity and collagen synthesis HGF (Hepatocyte Growth Factor) cell growth and tissue repair TGF- (Transforming Growth Factor Beta) tissue repair and regeneration These factors are literally the building blocks of collagen-rich connective tissue

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This induces the expression of genes such as GRP94, GRP78, and ERP57, accelerating the degradation of intracellular unfolded proteins and reducing ERS ( IRE1 is a type I transmembrane protein on the ER with endonuclease activity