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FIGURE 13 In the aforementioned study by Hsieh and collaborators (Hsieh et al., 2017) that focused on the ischemic muscle model (achieved via removal of the femoral artery), the pro-angiogenic effects of BPC 157 are evident, given the increased expression, internalization of vascular endothelial growth factor receptor 2 (VEGFR2), and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Jabbarzadeh Kaboli P., Afzalipour Khoshkbejari M., Mohammadi M., Abiri A., Mokhtarian R., Vazifemand R., Amanollahi S., Yazdi Sani S., Li M., Zhao Y., et al

This approach has shown promise in preclinical studies and is currently being evaluated in clinical trials for various types of cancer [5]

By doing so, they can enhance natural growth hormone levels, which can aid in muscle development, improve energy levels, support fat loss, and contribute to healthier skin and bones