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In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse happened when hydroxocobalamine was given intramuscularly

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The study found no impact on folate levels, but reported a 5% reduction in serum B12 levels when women went from 0 to 30 g of alcohol a day