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Chapter 36: Megaloblastic anemias: disorders of impaired DNA synthesis by Ralph Carmel "George H

It can also interfere with levodopa therapy if levodopa is taken without carbidopa, as vitamin B can diminish levodopas therapeutic effect

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- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)