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Ponadto wiatowa Agencja Antydopingowa (WADA) zakazuje go w sporcie

Patients with this condition or those with a family history suggestive of Lebers disease should avoid cyanocobalamin-containing products or use alternative forms of vitamin B12 such as hydroxocobalamin under careful medical supervision

When these compounds are put together into a solution that is injected into the bloodstream, it enters the body without any possibility of facing dilution or being inefficiently absorbed into the gut

Mechanistic studies have increasingly implicated nicotinamide adenine dinucleotide (NAD +), a central metabolic coenzyme, in the pathophysiology of fatty liver disease