In fact, PD-induced systemic inflammation was identified as a potential cause and/or non-traditional risk factor for CKD progression (Wahid et al., 2013)
In a pilot study in Thailand, Sangsuwan and Asawanonda tested the influence of daily intake of oral collagen (5 g) for 4 weeks on skin elasticity, especially in sun-exposed areas, in a randomized, double-blind, placebo-controlled trial (in a total of 36 women, aged 4060 years, where one-half of the participants were in the treatment group [ n = 18] or the placebo group [ n = 18]) [39]
Emerging evidence indicates that collagen-derived peptides can scavenge reactive oxygen species (ROS), enhance endogenous antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT), and thereby mitigate oxidative stress [73]
This initial turbulence could absolutely manifest as temporary insomnia or disturbed sleep architecture