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Background of the Pentose Phosphate Pathway (PPP) The pentose phosphate pathway (PPP) was first discovered and characterized in the 1930s by two prominent biochemists, Sir Hans Adolf Krebs and Fritz Albert Lipmann

But the greatest reduction in skin health is observed when women turn 50 years and experience menopause, which has a dramatic negative impact on skin aging owing to the loss of estrogen production from the ovaries, specifically the most potent estrogen in the body, which is 17-estradiol [2, 10, 14, 15]

Additionally, since the prostate gland secretes fluids that contribute to semen, and seminal fluid is deposited in the prostatic urethra by the vas deferens, PCa can result in difficulties achieving an erection, painful ejaculation, and other sexual dysfunctions

In research, Melatonin is studied for its potential effects on sleep regulation, antioxidant activity, immune modulation, and neuroprotection