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The abnormal expression of these neuropeptides and their receptors, besides their impact at the limbic system have emerged as pivotal factors for developing alcohol-related drinking behaviors and thereby, this knowledge has been used also to explain alcohol binge drinking patterns in adolescents (Crews et al., 2000

Pickel VM, Bourie F, Chan J, Mackie K, Lane DA, Wang G

Apart from this, the pivotal role of these cells is not simply associated with repairing and scarring process in case of brain injuries caused due to trauma, but also to safeguard the CNS by removal of waste or harmful metabolic substances [29, 32, 33]

Regulations change