The use of Rayyan ensured that two independent reviewers (RM, RC) screened titles and abstracts separately in blinded manner, meaning they were unaware of each others decisions, thereby minimizing selection bias
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Proceedings of the National Academy of Sciences 115(8):E1876-E1885. [doi.org]
Theres no hard biological ceiling on peptide count, but practical compliance breaks down above four compoundseach requires separate reconstitution, timing windows, storage, and injection sites