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535 p53 can accelerate ferroptosis and the development of atherosclerosis by binding to SLC7A11, preventing the synthesis of GSH, and increasing the hydrolysis of GSH and the production of ROS by activating glutaminase 2

responders may be identified as children with autism or ASD with lower plasma and/or intracellular levels of GSH, tGSH, or both, when compared to children without a diagnosis of autism

This degradation gives rise to trans-6-(4-hydroxy-3-methoxyphenyl)-2, 4-dioxo-5-hexanal, which then undergoes further cleavage to yield compounds like ferulic acid, feruloymethane, and vanillin (95)

IGFBP-3 is the major IGF-I binding protein