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In addition, this enzyme was also found in the nucleolus of various cell types, such as human HeLa cells, mouse L929 cells (fibroblast cell line), but also in mouse testes, specifically in spermatogonia, spermatocytes and spermatids

Here is what dermatologists commonly recommend: Prescription Topical Agents Dermatologists may prescribe a combination of hydroquinone (24%), tretinoin, and corticosteroids known as triple combination therapy

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10.1073/pnas.0437902100 144 DjerassiC