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While current treatment options for alcohol use disorder and depression exist, there is a need for more targeted strategies that address the underlying neurobiological mechanisms contributing to ethanol-induced depression

Injectable administration places the intact hexapeptide into subcutaneous adipose tissue, where it diffuses slowly into nearby capillaries and enters systemic circulation without encountering hepatic enzymes first

[10] These are the most speculative extensions of the systemic story: they rest on gene-signature matching and in-vitro observations, and they should be read as directions researchers find interesting rather than as demonstrated systemic effects

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