To prevent the degradation of Goralatide by serum enzymes, captopril was added at a concentration of 1 mM
The primary antibodies were rabbit anti-FGF5 antibody (Thermo Fisher Scientific, USA), goat anti-SRD5A1 antibody (Abcam, UK), rabbit anti-androgen receptor antibody (Abcam, UK), goat anti-DKK1 antibody (Abcam, UK), beta-catenin polyclonal antibody (Proteintech, USA), c-MYC polyclonal antibody (Proteintech, USA), and beta tubulin monoclonal antibody (Proteintech, USA)
Often, skipping one week or lowering the dose is enough to resolve the issue
There is also a ClinicalTrials.gov listing for a phase 1 study described as assessing safety and pharmacokinetics of BPC-157 in healthy volunteers