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Vitamin B12 toxicity is not typically an issue as it is water soluble, and any excess is excreted in the urine

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National Library of Medicine: "B Vitamins" Mayo Clinic: "Biotin (Oral Route)" FDA: FDA 101: Dietary Supplements Mayo Clinic: "Anaphylaxis" Mayo Clinic: "Niacin" Mayo Clinic: "Allergies" Vitamin B12 - "Health Professional Fact Sheet" National Institutes of Health: "Vitamin B12 - Health Professional Fact Sheet" Journal of Allergy and Clinical Immunology: Vitamin B12 Hypersensitivity: A Retrospective Multicenter Study Justin Laube, MD Medical Reviewer Justin Laube, MD, is a dual board-certified integrative and internal medicine physician, retreat leader, and healing educator with over 15 years of experience caring for patients w

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