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Together, these findings demonstrate that, in contrast with acute exposure, chronic disruption of iron homeostasis with consequent GSH depletion remodels cellular redox homeostasis over time, inducing a state we term chronoferroptosis: a persistent ferroptotic adaptation characterized by coordinated alterations in iron-handling and antioxidant defense proteins that may represent early vulnerability to neurodegenerative pathology

In this approach, a recombinant protein of interest is commonly fused to a variety of tags (including the His6-tag, maltose-binding protein, and GST) to detect, purify, and pull down the interacting partners of a protein of interest

Personal genomes: The case of the missing heritability

This direct administration method offers distinct advantages for specific populations and circumstances