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In skin and tendon studies, it creates more organized, mature collagen formation compared to controls and consistently reduces scarring

However, fracture hematoma formation important first healing step, excessive anticoagulation potentially problematic

With physician-compounded topical formulations used daily, patients consistently report improved skin texture and smoothness at weeks 2 to 4, increased firmness and reduced fine line visibility at weeks 6 to 10, better hydration and radiance that holds with continued use, and a gradual improvement in skin tone evenness over 3 to 6 months

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