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3 In one study, people with type 2 diabetes who took tesamorelin, a synthetic peptide that mimics growth hormone-releasing hormone (GHRH), experienced a significant reduction in visceral adipose tissue, the deep belly fat that surrounds internal organs and contributes to higher metabolic and cardiovascular risk

In the trial-product estimand, 19.3% of participants achieved a reduction of at least 30% in body weight

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5.2 Ferroptosis of macrophage promotes atherosclerosis Macrophage death exhibits a dual role in atherogenesis