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JP patent 59,151,894 Kono G, Harada M, Sugisaki K, Nishida M (1977) High glutathione-containing yeast

[31] developed a hydroquinone-induced C57BL/6 mouse model, in which topical application of apigenin increased melanin content in hair follicles by enhancing TYR expression, and promoting melanin synthesis

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All sample extracts were profiled using an Exon UHPLC system (AB Sciex, USA) coupled to an AB Sciex X500R Q-TOF-MS system (Sciex technologies, Canada), equipped with a DuoSpray ion source